Time to Analgesia Onset and Pharmacokinetics After Separate and Combined Administration of Liposome Bupivacaine and Bupivacaine HCl: Considerations for Clinicians

Fig. (2) Bupivacaine exposure during the first 24 hours after administration (AUC_0-24) as a percentage of total exposure (AUC_0-∞) (Unpublished data). AUC_0-24 = area under the concentration time curve from time zero to 24 hours post-dose; AUC_0-∞ = area under the concentration time curve from time zero to infinity; IHR = inguinal hernia repair; SD = standard deviation; TKA = total knee arthroplasty.