Effect of a Type II Collagen Fragment on the Expression of Genes of the Extracellular Matrix in Cells of the Intervertebral Disc

Fig. (1) Effect of the CII (245-270) peptide on the gene expression of aggrecan (AGG) and type II collagen (Col2). AF and NP cells were incubated in the absence (Control (Ctl);-○-) or the presence of the CII (245-270) peptide (-●-). Agarose gels are representative of 3 experiments while quantitative results are the mean ± SE of 3 experiments normalized to18S RNA content.