Table 1: Immunhistochemical Marker Used to Narrow Down the Differential Diagnosis

Antigen Present Patient Interpretation
β-Catenin ++ up regulated in desmoplastic fibroma [16] and aggressive fibromatosis [17]
S-100 + ubiquitary present protein (glia cells, adipocytes, melancytes, chondrocytes)
actin (+) nucleus ubiquitary present protein (mainly myocytes). Together with Desmin up regulated in leiomyosarcoma
KiM1P (+) nucleus present in histiocytes
MDM 2 (+) nucleus Together with MDM 2 and CDK4 upregulated in liposarcoma
CD31/CD34 - up regulated in angiogenesis
MyoD1 - up regulated in rhabdomysarcoma
myogenin - up regulated in rhabdomysarcoma
desmin - up regulated in leiomysarcoma
CDK4 - up regulated in liposarcoma
DOG1 - up regulated in GIST
Ki67 positive in 2% of cells up regulated in proliferating cells