Table 2: Elution Pharmacokinetics and Standard Deviation of Vancomycin from Cerasorb® and Cerasorb M®. Antibiotic Release
is Expressed in µg /ml. Mean Values were Derived from a Total of 4 Different Tests. Granules were Loaded in a Solution
of 50 g/L Antibiotics
|
Elution Kinetics of Vancomycin |
| Day 1 |
Day 2 |
Day 3 |
Day 4 |
Day 5 |
Day 6 |
Day 7 |
Day 8 |
Day 9 |
Day 10 |
| Cerasorb |
1761.3 |
277.35 |
37.875 |
5.4 |
1.25 |
1 |
0.9 |
0.9 |
0.9 |
0.925 |
| standard deviation |
331.87 |
32.46 |
2.55 |
0.41 |
0.25 |
0.2 |
0 |
0 |
0 |
0.05 |
| Cerasorb M |
182.775 |
30.55 |
3.475 |
1.175 |
1.175 |
1.05 |
1.2 |
1.125 |
1.125 |
1.075 |
| standard deviation |
27.9 |
23.4 |
0.56 |
0.4 |
0.3 |
0.3 |
0.38 |
0.45 |
0.45 |
0.35 |
| detection treshold |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |