Fig. (4) Effects of Phyllanthus fraternus extract on paw withdrawal latency to mechanical stimuli in chronic inflammatory muscle hyperalgesia on the ipsilaterally (A) and contra lateral side (B). The mean thermal withdrawal latency (in seconds) was measured for both the paws ipsilateral and contralateral in rats (n=5 per group). Each point represents mean ± standard error of mean of the paw withdrawal threshold (in grams) to mechanical stimulation by von Frey filaments. Data were analyzed by one-way analysis of variance using Dunnett’s multiple comparison test. p<0.05 was considered significant as compared with the inflammatory control.