Table 1: Insecticides evaluated for larvicidal activity against Aedes aegypti (Data procured from IRAC).

Insecticide IUPAC name Structure Mode of action Percent purity
Organochlorines
Lindane (1r,2R,3S,4r,5R,6S)-1,2,3,4,5,6-hexachlorocyclohexane Inhibit gamma-Aminobutyric acid (GABA) chloride ionophore complex 99.5
Endosulphan 6,7,8,9,10-Hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepine-3-oxide Inhibit gamma-Aminobutyric acid (GABA) chloride ionophore complex 96.5
Organophosphates
Malathion Diethyl 2-[(dimethoxyphosphorothioyl) sulfanyl] butanede Inhibit acetylcholine esterase enzyme 95.0
Fenitrothion O,O-Dimethyl O-(3-methyl-4-nitrophenyl) phosphorothioatek Inhibit acetylcholine esterase enzyme 96.7
Carbamates
Carbofuran 2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Inhibit acetylcholine esterase enzyme 98.0
Fenobucarb 2-Butan-2-ylphenyl) N-methylcarbamate Inhibit acetylcholine esterase enzyme 95.0
Pyrethroids
Lambda-cyhalothrin 3-(2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethyl-cyano(3-phenoxyphenyl) methyl cyclopropanecarboxylate Modulate sodium channels 98.0
Alpha-cypermethrin [Cyano-(3-phenoxyphenyl) methyl] 3-(2,2-dichloropropane-1-carboxylate Modulate sodium channels 97.0
Permethrin (±)-3-Phenoxybenzyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate Modulate sodium channels 94.0
Deltamethrin [(S)- Cyano-(3-phenoxyphenyl)-methyl] (1R,3R)-3-(2,2-dibromoethenyl)-2,2-dimethyl-cyclopropane-1-carboxylate Modulate sodium channels 98.0
Neonicotinoid
Acetamiprid N-[(6- chloro-3-pyridyl) methyl]-N’-cyano-N-methyl-acetamidine Compete with nicotinic acetylcholine receptors 99.9
Alkaloid-Secondary metabolite
Berberine 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium Singlet oxygen generation effect DNA Pol-I 95.0
Avermectin
Emamectin benzoate 4′′-Deoxy-4′′-epi-methylamino-avermectin
(Medical Subject Heading -MeSH)
Modulate glutamate gated chloride channels (allosteric modulators) 99.3