Table 1: Membrane lipids.

Classification Commentary References
Phospholipids Phosphatidylcholine
(lecitine)

The phospholipids constitute a solvent for proteins, the nature of their fatty acids then the length and saturation of the carbon chain determine the fluidity of the membrane and condition these physiological properties. Phosphatidylserine and phosphatidylinositol are essential for the invasion of erythrocytes by Plasmodium. During the parasite invasion, proteins secreted by the apical organelle of the merozoite interact specifically with the phospholipids of the erythrocyte membrane.
[79-86]
Phosphatidylethanolamine (cephaline)
Phosphatidylserine
Phosphatidylinositol
Sphingomyelin
Glycolipids Glycosphingolipids
(ganglioside)

Glycolipids play an essential role in the molecular recognition of cell membrane. Upon invasion of the host cells, the proteins of the apical organelle of Plasmodium bind to the erythrocyte via the glycolipids. Plasmodium falciparum proteins located in the microneme of the merozoite bind to erythrocyte membrane via glycosylphosphatidylinositol.
[87-90]
Glycoglycerolipids
(galactolipide)
Glycophosphatidylinositols
Cholesterol Cholesterol contributes to the stability and fluidity of cell membrane by intercalating between the phospholipids. In the plasma membrane, it forms the lipid raft (Detergent-Resistant Membrane (DRM)). DRM is a microdomain rich in cholesterol and sphingolipids, essential for the anchoring of proteins. DRM has an essential role in cellular communication. The mechanisms regulated by DRM are responsible for the uptake of host proteins and maintenance of intracellular PVM in the non-endocytic RBC. [91-93]