Table 3: Base-case probabilistic results over a 5 and 10 years’ time horizon.
| Strategy |
Average Cost Per Patient (£) |
Incremental Cost (£) |
Average QALYs Per Patient (£) |
Incremental QALYs |
ICER (£) (∆Cost/∆QALYs) |
Probability Cost-Effective for Different WPT Thresholds (%) |
| £20,000 |
30,000 |
|
Base-case analysis- Informing the clinical effectiveness input parameters using results from the UK based study- 5 years’ Time horizon
|
| MCWP |
20,211 |
- |
1.65 |
- |
- |
- |
- |
| The Vest™ system |
14,176 |
-6,035 |
1.72 |
+ 0.07 |
Dominant |
98% |
99% |
|
Base-case analysis- Informing the clinical effectiveness input parameters using results from the UK based study- 10 years’ Time horizon
|
| MCWP |
£34,632 |
- |
3.03 |
- |
- |
- |
- |
| The Vest™ system |
£24,108 |
-10,524 |
3.23 |
0.19 |
Dominant |
98% |
100% |
|
Sensitivity analysis- Informing the clinical effectiveness input parameters using results from study by Yuan et al. 2010- 5 years’ Time horizon
|
| MCWP |
£14,835 |
- |
1.77 |
- |
- |
- |
- |
| The VestTM system |
££9,108 |
-£5,727 |
1.90 |
0.14 |
Dominate |
100% |
100% |
|
Sensitivity analysis- Informing the clinical effectiveness input parameters using results from study by Lechtzin et al. 2016- 5 years’ Time horizon
|
| MCWP |
£20,211 |
- |
1.65 |
- |
- |
- |
- |
| The VestTM system |
£17,618 |
-£2,593 |
1.69 |
0.03 |
Dominate |
100% |
100% |
MCWP: Manual Chest Wall Physiotherapy; QALY: Quality adjusted life years