S.No. | Parameter | TMZ Solution | TMZ SLNs’ | P-80 coated SLNs’ |
---|---|---|---|---|
1 | MRT (h) | 3.78±0.03 | 45.32±0.82 | 57.89±0.45 |
2 | AUC (h ng ml-1) | 807.63±2.4 | 7305.67±4.2 | 9605.84±3.7 |
3 | C max (ng ml−1) | 376.2±3.5 | 200.1±3.9 | 157.66±2.4 |
4 | CL (mg kg−1/h ng ml−1) | 0.0124±0.0001 | 0.0014±0.0001 | 0.0006±0.0001 |