Table 2: Various pharmacokinetic parameters of different formulations.

S.No. Parameter TMZ Solution TMZ SLNs’ P-80 coated SLNs’
1 MRT (h) 3.78±0.03 45.32±0.82 57.89±0.45
2 AUC (h ng ml-1) 807.63±2.4 7305.67±4.2 9605.84±3.7
3 C max (ng ml−1) 376.2±3.5 200.1±3.9 157.66±2.4
4 CL (mg kg−1/h ng ml−1) 0.0124±0.0001 0.0014±0.0001 0.0006±0.0001

(mean ±S.D; n=3)