Table 2: Concentration of piperaquine at day 60.

No Reference Sites Study population Dose regimen Malaria infection Conc. Day 60 (approximate minimum-maximum)
1 [47] Pooled analysis Pooled analysis Pooled analysis Pf & healthy volunteers >1 ng/ml
(±1.6-20 ng/ml)
2 [52] - adults Single dose Healthy <1 ng/ml (±0.3-0.9 ng/ml)
3 [52] - adults 3 days dose Healthy >1 ng/ml (±4-7 ng/ml)
4 [53] Thailand adults 3 days dose Pf >1 ng/ml (±1.15-17 ng/ml)
5 [54] Thailand Children and adults 3 days dose Pf & Pv Pf: 1.2 ng/ml
Pv: 1.3 ng/ml
6 [55] Vietnam adults 3 days dose Healthy 6 ng/ml

*Pf = Plasmodium falciparum
Pv = Plasmodium vivax