Clinical/Laboratory Data | Overall Total | Adrenal Sufficiency | Adrenal Insufficiency | P-value |
---|---|---|---|---|
Baseline Serum Cortisol Levels (mmol/L), MD (IQR) | 398.0 (255.0, 509.0) |
473.0 (355.0, 573.) |
255.0 (168.0, 343.0) |
<0.0001 |
Post-Injection Serum Cortisol Levels (mmol/L), MD (IQR) | 537.0 (453.0, 632.0) |
606.0 (543.0, 674.0) |
425.5 (392.5, 464.0) |
<0.0001 |
Δ Serum Cortisol Levels (mmol/L) M±SD | 147.3 ± 122.7 | 150.2 ± 117.0 | 142.1 ± 142.1 | 0.7980 |
Sodium (mmol/L), MD (IQR) | 135.0 (131.0, 139.0) |
135.0 (130.0, 139.0) |
137.0 (133.0, 139.0) |
0.2488 |
Potassium (mmol/L), M± SD | 3.99 ± 0.77 | 6.0 ± 2.9 | 5.5 ± 1.8 | 0.3486 |
Fasting serum Glucose (mmol/L), MD (IQR) | 5.1 (4.6, 6.1) | 5.5 (4.7, 6.4) | 4.9 (4.4, 5.5) | 0.1705 |
CD4 count MD (IQR) | 187.0 (42.0, 565.0) |
125.5 (29.0, 456.0) |
197.0 (44.0, 713.0) |
0.4522 |
Lipoarabinomannan (LAM), MD (IQR) | 1.0 (1.0, 1.0) |
1.0 (1.0, 1.0) |
1.0 (1.0, 1.0) |
0.8647 |
GeneXpert- Positive Results, n (%) | 13 (16.7) | 7 (14.9) | 6 (21.1) | 0.4672 |
Burden of Symptoms, M± SD | 4.8 ± 2.4 | 4.6 ± 2.4 | 5.3 ± 2.4 | 0.2091 |
Burden of Signs, M± SD | 4.9 ± 1.4 | 5.0 ± 1.5 | 4.9 ± 1.2 | 0.7204 |
Burden of Signs & Symptoms, M± SD | 9.6 ± 3.2 | 9.5 ± 3.1 | 10.1 ± 3.1 | 0.4235 |