Table 12: Difference factor (f1) values.

Reference Standard (Herbesser® table)t Vs Test Formulations Difference factor (f1) values
Herbesser® tablet/Diltiazem Hydrochloride and Ethocel 45Premium (10:1) 65
Herbesser®  tablet /Diltiazem Hydrochloride and Ethocel 45Premium (10:2) 62
Herbesser® tablet /Diltiazem Hydrochloride and Ethocel 45Premium (10:3) 67
Herbesser®  tablet /Diltiazem Hydrochloride and K100 LV Methocel tablets (10:1) 70
Herbesser® tablet /Diltiazem Hydrochloride and K100 LV Methocel tablets (10:2) 65
Herbesser® tablet /Diltiazem Hydrochloride and K100 LV Methocel tablets (10:3) 72
Herbesser® tablet /Diltiazem Hydrochloride and K15M EP Methocel Premium tablets (10:1) 70
Herbesser®  tablet /Diltiazem Hydrochloride and K15M EP Methocel Premium tablets (10:2) 68
Herbesser®  tablet /Diltiazem Hydrochloride and K15M EP Methocel Premium tablets (10:3) 65
Herbesser® tablet /Diltiazem Hydrochloride and Ethocel 45Premium tablets (10:1) having Co-excipient (HPMC) 34
Herbesser®  tablet /Diltiazem Hydrochloride and Ethocel 45Premium tablets (10:2) having Co-excipient (HPMC) 32
Herbesser®  tablet /Diltiazem Hydrochloride and Ethocel 45Premium tablets (10:3)  having Co-excipient (HPMC) 35
Herbesser®  tablet /Diltiazem Hydrochloride and Ethocel 45Premium tablets (10:1) having Co-excipient (CMC-Na) 33
Herbesser® tablet /Diltiazem Hydrochloride and Ethocel 45Premium tablets (10:2) having Co-excipient (CMC-Na) 31
Herbesser®  tablet /Diltiazem Hydrochloride and Ethocel 45Premium tablets  (10:3) having Co-excipient (CMC-Na) 35
Herbesser®  tablet /Diltiazem Hydrochloride and Ethocel 45Premium tablets (10:1)  having Co-excipient (Starch) 37
Herbesser® tablet /Diltiazem Hydrochloride and Ethocel 45Premium tablets (10:2)  having Co-excipient (Starch) 34
Herbesser® tablet /Diltiazem Hydrochloride and Ethocel 45Premium tablets  (10:3) having Co-excipient (Starch) 32