Formulation and In-Vitro Evaluation of Controlled Release Matrix Tablets of Diltiazem Hydrochloride Using Different Rate Controlling Polymers

Table 4: Composition of 100mg diltiazem hydrochloride and ethocel 45 premium matrix tablets having co-excipients (Starch or HPMC or Na-CMC).

Drug to Polymer Ratio	Diltiazem Hydrochloride	Polymers Ethocel 45 Premium	Co-excipients (Starch or HPMC or Na-CMC)	Lubricant Magnesium Stearate (0.5%)	Filler (Lactose)
10:1	30mg	3mg	21.39mg	0.5mg	46.55mg
10:2	30mg	6mg	19.05mg	0.5mg	44.45mg
10:3	30mg	9mg	18.15mg	0.5mg	42.35mg