Table 7: Results of Solubility studies of Diltiazem Hydrochloride.

S. No Solvent Temperature Solubility
1 Phosphate buffer (6.8pH) 25 °C 0.8mg/ml
2 Phosphate buffer (6.8pH) 37 °C 0.86mg/ml
3 Phosphate buffer (6.8pH) 40 °C 0.89mg/ml
4 Phosphate buffer (7.4pH) 25 °C 0.98 mg/ml
5 Phosphate buffer (7.4pH) 37 °C 1mg/ml
6 Phosphate buffer (7.4pH) 40 °C 1mg/ml
7 Distilled Water 25 °C 0.986 mg/ml
8 Distilled Water 37 °C 0.987 mg/ml
9 Distilled Water 40 °C 0.99 mg/ml