| Formulations |
Thickness (mm) |
Diameter (mm) |
Hardness (kg/cm2) |
Friability (%) |
|---|---|---|---|---|
| Diltiazem Hydrochloride and Ethocel 45Premium | 2.6 ±0.06mm | 8.0 mm | 6.5±0.05 | 0.08%±0.18 |
| Diltiazem Hydrochloride and K100 LV Methocel | 2.7 ±0.12mm | -do- | 6.98±0.13 | 0.16%±0.03 |
| Diltiazem Hydrochloride and K15M EP Methocel Premium | 2.8 ±0.07mm | -do- | 6.82±0.24 | 0.18%±0.06 |
| Diltiazem Hydrochloride and Ethocel 45Premium with Co-excipient (Starch) | 2.7 ±0.09mm | -do- | 6.79±0.09 | 0.21%±0.23 |
| Diltiazem Hydrochloride and Ethocel 45Premium with Co-excipient (Na-CMC) | 2.8 ±0.21mm | -do- | 6.86±0.018 | 0.23%±0.09 |
| Diltiazem Hydrochloride and Ethocel 45Premium with Co-excipient (HPMC) | 2.9 ±0.15mm | -do- | 7.0±0.02 | 0.19%±0.12 |