Table 1: Biological distribution of 99mTc-salmeterol xinafoate complex in mice as a function of time.
| Organs and body fluids |
% Injected dose/organ and body fluid at different times post injection (min) |
| 5 |
30 |
60 |
120 |
240 |
| Bone |
16.2 ± 1.1 |
36.5 ± 3.6 |
33.85 ± 3.6 |
29.3 ± 1.9 |
25.1±2.3 |
| Muscles |
14.25 ± 0.9 |
8.05 ± 0.5 |
4.56 ± 0.2 |
2.24 ± 0.1 |
2.11±0.1 |
| Kidneys |
6.38 ± 0.2 |
7.23± 0.6 |
8.67 ± 0.6 |
10.2 ± 0.8 |
11.23±0.0 |
| Blood |
22.76 ± 1.9 |
13.75± 1.1 |
6.48 ± 0.1 |
2.85 ± 0.1 |
0.62±0.0 |
| Intestine |
5.5 ± 0.02 |
5.55± 0.2 |
10.65 ± 0.9 |
14.93±0.7 |
16.1±1.0 |
| Liver |
5.47± 0.3 |
5.83± 0.3 |
6.31 ± 0.2 |
9.17±0.3 |
11.09±0.2 |
| Stomach |
2.34 ± 0.1 |
2.52± 0.1 |
6.39 ± 0.1 |
6.45±0.3 |
7.43±0.5 |
| Lungs |
5.78 ± 0.3 |
3.92± 0.2 |
2.72 ± 0.1 |
1.02±0.0 |
0.8±0.1 |
| Spleen |
3.85 ± 0.2 |
0.63± 0.0 |
0.36 ± 0.0 |
0.23±0.0 |
0.20±0.0 |
| Heart |
2.05 ± 0.0 |
0.63± 0.0 |
0.46 ± 0.0 |
0.19 ±0.0 |
0.06±0.0 |
| Urine |
14.36 ± 0.5 |
15.18± 1.3 |
19.01 ± 1.1 |
23.35±1.3 |
25.07±1.3 |