Table 5: Physiochemical properties of buccal tablets in main study.
| Formulation code |
Hardness (kg/cm2) |
Thickness (mm) |
Weight variation (mg) |
Diameter (mm) |
Surface pH |
Friability (%) |
Mucoadhesive time (h) |
| F14 |
7.2 |
3.0±0.32 |
503.0±2.14 |
12.1±0.01 |
6.5 |
0.6 |
4.3 |
| F15 |
7.1 |
3.5±0.09 |
493.5±1.84 |
12±0.05 |
6.0 |
0.4 |
3.6 |
| F16 |
7.4 |
3.2±0.09 |
490.8±1.56 |
12±0.03 |
5.5 |
0.6 |
4.3 |
| F17 |
8.0 |
3.2±0.23 |
495.4±2.11 |
11.5±0.01 |
7.0 |
0.4 |
2.7 |
| F18 |
7.3 |
3.2±0.08 |
497.1±1.23 |
12.1±0.01 |
5.5 |
0.5 |
2.9 |
| F19 |
7.7 |
3.1±0.09 |
492.6±0.98 |
12.2±0.01 |
5.5 |
0.6 |
4.8 |
| F20 |
8.1 |
3.0±0.04 |
491.4±3.12 |
12±0.01 |
6.0 |
0.7 |
2.7 |
| F21 |
6.8 |
3.0±0.03 |
500.5±1.87 |
12±0.03 |
5.2 |
0.2 |
4.0 |
| F22 |
8.0 |
3.0±0.04 |
492.3±1.19 |
12±0.03 |
6.0 |
0.6 |
4.0 |
| F23 |
8.0 |
3.0±0.008 |
493.3±2.21 |
11±0.01 |
6.2 |
0.6 |
4.7 |
| F24 |
8.1 |
3.2±0.08 |
496.2±3.26 |
11±0.01 |
6.0 |
0.4 |
2.3 |
Thickness and diameter were calculated as mean ± SD of 10 tablets whereas weight variation was performed on 20. (SD = standard deviation).