Table 1: Clinical Characteristics of Patients at Study Entry

Age, years (median, range) 49, 36-62
Women 8 (80%)
Duration of RA, years 8, 1-19
TJC, median (IQR) 23 (17.5)
SJC, median (IQR) 11.5 (6.25)
HAQ-DI, median (IQR) 2.1 (0.67)
FACIT-F, median (IQR) 27.0 (10.8)
DAS28, median (IQR) 7.2 (1.2)
CRP, median (IQR) (mg/L) 33.1 (71.6)
ESR, median (IQR) (mm/hr) 108 (43.5)
Anti-CCP titer, median (IQR) 76 (225)
No. of patients with baseline radiographic erosions 7 (70%)
Median number of failed DMARDs 4
No. of patients who failed anti-TNFα treatment 2 (20%)

RA = rheumatoid arthritis; TJC = tender joint count; SJC = swollen joint count; HAQ = Health assessment questionnaire; FACIT-F = Functional Assessment of Chronic Illness Therapy-Fatique; DAS = disease activity score; CRP = C-reactive protein; ESR = erythrocyte sedimentation rate; CCP = citrullinated cyclic peptide; DMARD = disease modifying anti-rheumatic drugs; TNF = tumor necrosis factor.