Table 2: Differentially expressed genes in PC-treated via untreated OA chondrocytes.

Gene ID Gene
Identifier
Fold
change*
Description
Inflammatory response
FABP4 NM_001442 -2.11 Fatty acid binding protein 4, adipocyte
IRAK2 AI246590 -1.71 Interleukin-1 receptor-associated kinase 2
IL1RAP AF167343 -1.57 Interleukin 1 receptor accessory protein
BMP2 NM_001200 -1.55 Bone morphogenetic protein 2
B4GALT1 M22921 2.20 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
FN1 AJ276395 1.92 Fibronectin 1
Skeletal system development
DLX2 NM_004405 -2.37 Distal-less homeobox 2
PCGF2 NM_007144 -1.89 Polycomb group ring finger 2
EPHA2 NM_004431 -1.69 EPH receptor A2
POSTN AW137148 -1.56 Periostin, osteoblast specific factor
BMP2 NM_001200 -1.55 Bone morphogenetic protein 2
FGFR2 M80634 1.99 Fibroblast growth factor receptor 2
TGFBR1 AV700621 1.74 Transforming growth factor, beta receptor 1
RDH10 NM_172037 1.62 Retinol dehydrogenase 10 (all-trans)
Wnt receptor
signaling pathways
APCDD1 N48299 -2.68 Adenomatosis polyposis coli down-regulated 1
NDP NM_000266 -2.30 Norrie disease (pseudoglioma)
CCND1 BC000076 -1.68 Cyclin D1
SOX4 AI989477 -1.67 SRY (sex determining region Y)-box 4
FZD8 AB043703 -1.58 Frizzled homolog 8 (Drosophila)
BMP2 NM_001200 -1.55 Bone morphogenetic protein 2
FGFR2 M80634 1.99 Fibroblast growth factor receptor 2
SMAD3 BF971416 1.55 SMAD family member 3

*Negative number indicates decreased expression and positive number indicates increased expression (fold change) in the PC-treated OA chondrocyte compared with the untreated OA chondrocytes.