Table 2: Demographic, clinical and serological data of the RA subgroups.
|
Remission |
Mild Disease Activity |
Moderate Disease Activity |
Severe Disease Activity |
P value |
Age |
36.53±11.03 |
38.87 ±8.11 |
38.18 ±7.87 |
35.87 ±7.09 |
NS |
Gender (female no& %) |
14(93.33%) |
13(86.67%) |
35(92.11%) |
13(86.67%) |
NS* |
BMI |
29.57 ±6.99 |
28.43 ±7.45 |
28.12 ±8.31 |
26.75± 9.22 |
NS |
Disease duration |
39.40±19.67 |
40.93±20.78 |
37.58±14.27 |
36.87±16.70 |
NS |
DAS 28 SCORE |
1.94±0.19 |
2.86±0.28 |
4.05±0.53 |
5.38±0.10 |
<0.0001 |
ESR |
24.33±15.48 |
36.87±34.67 |
43.08±25.40 |
51.40±22.16 |
<0.0001 |
CRP |
3.01±1.35 |
6.80±2.20 |
11.71±7.65 |
43.30±30.61 |
<0.0001 |
RF |
20.44±15.48 |
33.87±34.67 |
50.19±42.78 |
112.55±86.79 |
<0.0001 |
ACPA |
26.25±24.99 |
19.69±24.18 |
21.86±28.05 |
35.56±41.82 |
NS |
ESM1 |
1374.54±556.12 |
1561.47±434.91 |
2989.01±647.84 |
4565.37±437.88 |
<0.0001 |
HAQ-DI |
0.13± 0.35 |
0.40± 0.63 |
1.60± 0.72 |
2.93 ± 0.26 |
<0.0001 |
Modified Larsen score |
0.4 ±0.62 |
1.07 ±0.59 |
1.87± 0.66 |
3.00± 0.53 |
<0.0001 |
BMI = Body Mass Index, ESR = Erythrocyte Sedimentation Rate, CRP = C Reactive Protein, RF = Rheumatoid Factor, ACPA = Anti-Citrullinated Peptide Antibody, ESM-1 = Endothelial Cell Specific Molecule 1, DAS = Disease Activity Score.*= Chi- Square test. HAQ-DI = The Health Assessment Questionnaire Disability Index. NB: P value between patients with severe disease activity and remission only.