Table 1: Rheumatology biologic therapies approved in Saudi Arabia [29].

Scientific Name Trade Name Year of
Mechanism of Action
Abatacept Orencia IV: 2010
SC: 2014
Selective T-cell co-stimulation modulator
Adalimumab Humira 2005 TNF inhibitor
Etanercept Enbrel 2006 TNF inhibitor
Golimumab Symponi 2015 TNF inhibitor
Infliximab Remicade 2011 TNF inhibitor
Remsima 2016
Rituximab MabThera 2008 Targets CD20 on B cells
Tocilizumab Actemra IV: 2014
SC: 2017
IL-6 receptor antagonist
*Provided by the respective manufacturer.
IL, interleukin; IV, intravenous; SC, subcutaneous; TNF, tumor necrosis factor.