Table 5: Association of the XRCC3 Thr241Met polymorphism with clinical and laboratory variables.

Variables
Polymorphism Genotypes Yes (%) No (%) Pa OR (IC 95%)b
Anti-Dna (ds)
XRCC3 codon 241
Thr→Met
Thr/Thr
Thr/Met
Met/Met
Thr/Met + Met/Met
8
5
1
6
35
16
5
21
Reference
0.74
1
0.76
1
1.37 (0.39 – 4.84)
0.88 (0.90 – 8.56)
1.25 (0.38 – 4.10)
Leukopenia
XRCC3códon 241
Thr→Met
Thr/Thr
Thr/Met
Met/Met
Thr/Met + Met/Met
14
10
1
11
29
11
5
16
Reference
0.28
0.65
0.61
1.88 (0.65 – 5.48)
0.41 (0.04 – 3.89)
1.42 (0.52 – 3.86)
Cutaneous Lupus
XRCC3códon 241
Thr→Met
Thr/Thr
Thr/Met
Met/Met
Thr/Met + Met/Met
13
6
1
6
30
15
5
21
Reference
1
0.66
0.58
1
0.92 (0.29 – 2.91)
0.46 (0.049 - 4.35)
0.66 (0.21 – 2.01)

aFisher’s test; bOR, odds ratio.