Table 1: Biochemical markers measured in Inflammatory Bowel Disease patients and controls, their analytical Method, their normal range and their unit.

Biochemical Markers	Analytical Method	Normal Range	Unit
Calcium	Colorimetric Arsenazo [13]	2,2 - 2,6 [13]	mmol/l
Phosphorus	Colorimetric phosphomolybdate complex [14]	0,5 - 2 [14]	mmol/l
Alcaline phosphatase	Kinetic rate method [15]	38 - 126 [15]	UI/L
Creatinine	Jaffe method [16]	Male (70-120) Female (60-110) [16]	µmol/l
Erythrocyte sedimentation rate	Wintrobe method	Male = age/2 Female = age + 10/2	mm
25-OH Vitamin D	Electro-chimiluminescence immunoassy ECLIA [17]	≥ 30 [17-20]	ng/ml
Parathyroid hormone	Electro-chimiluminescence immunoassy ECLIA [21]	15 - 65 [21]	pg/ml
Serum osteocalcin	Electro-chimiluminescence immunoassy ECLIA [22]	Female: Premenopausal female: 11 - 43 Menopausal female:15 - 46 Osteoporotic: 13 - 48 Male: 18 à < 30 years: 24 à 70 30 à 50 years: 14 à 42 > 50 à 70 years: 14 à 46 [22]	ng/ml
Urinary Cross Laps	ELISA immunoassay [23]	Menopausal female: 67-544 Premenopausal female: 121-874 Male: 54-559 [23]	µg/mmol urinary creatinine
Albumin	Colorimetric bichromatic digital endpoint methodology [24]	34-48 [24]	g/l