TREATMENT | DOSE | 14 DAY | 16 DAY | 18 DAY | 20 DAY | 22 DAY |
---|---|---|---|---|---|---|
Vehicle | 1 ml | 1.90±0.0150 | 3.15±0.0250 | 3.98±0.0141 | 4.49±0.0095 | 4.92±0.0221 |
Standard (IND) | 10 mg/kg | 0.83±0.0095*,# | 1.52±0.0263*,# | 1.69±0.0095*,# | 1.26±0.0125*,# | 0.93±0.0208*,# |
CPE | 200 mg/kg | 1.49±0.02348*,# | 2.42±0.0129*,# | 2.99±0.0170*,# | 2.66±0.0182*,# | 2.19±0.0129*,# |
SGE | 200 mg/kg | 1.62±0.0170* | 2.71±0.0170* | 3.23±0.0095* | 2.96±0.0129* | 2.49±0.0129* |