Table 3: Literature Summary: SLE Peripartum Flares and Pregnancy Outcomes Presented in Mean % ± SEM and Median % with Interquartile Range (IQR) for Each Time Period

N Mean ± SEM % Median ± IQR % p-Value Between Groups


Flares during pregnancy		 <1990 13 25.9 ± 2.9 25.0 ± 10.4

0.002
1991-1998 11 41.8 ± 4.8 44.4 ± 25.6
>1999 14 20.7 ± 4.0 16.0 ± 9.1


Flare-up postpartum		 <1990 8 16.3 ± 4.0 15.0 ± 22.3

NS
1991-1998 8 13.3 ± 3.4 11.8 ± 16.23
>1999 8 6.3 ± 2.2 6.6 ± 10.1


Total flares		 <1990 13 35.9 ± 5.0 34.0 ± 27.2

0.002
1991-1998 12 51.4 ± 6.0 52.5 ± 31.1
>1999 14 24.3 ± 4.1 20.5 ± 20.0


Elective termination		 <1990 13 15.3 ± 2.5 15.6 ± 13.4

NS
1991-1998 14 9.7 ± 2.5 7.9 ± 10.7
>1999 17 7.5 ± 2.5 6.7 ± 9.1


Fetal wastage		 <1990 15 23.0 ± 3.5 17.9 ± 30.0

NS
1991-1998 13 18.9 ± 2.5 19.4 ± 15.5
>1999 17 16.8 ± 2.1 17.0 ± 15.1


Prematurity		 <1990 11 19.1 ± 4.4 12.5 ± 25.3

NS
1991-1998 15 31.4 ± 3.5 27.0 ± 25.7
>1999 17 24.5 ± 3.2 21.0 ± 17.7


Full term birth		 <1990 12 50.4 ± 5.7 57.5 ± 35.6

NS
1991-1998 15 43.3 ± 3.2 42.6 ± 25.6
>1999 17 52.9 ± 4.1 53.3 ± 25.7


Live birth		 <1990 16 64.9 ± 3.7 65.2 ± 23.6

0.024
1991-1998 16 74.5 ± 2.7 75.5 ± 21.3
>1999 18 77.0 ± 3.1 78.2 ± 20.8

N= number of publications, NS=non-significant.