Melatonin and Its Day and Night Rhythm of Alterations in Familial Mediterranean Fever: A Brief Research Letter

Table 2: Melatonin Levels in Patients with FMF and Healthy Controls

	Melatonin Levels (pg/ml)^*
	in Acute Attack	at 03.30 am	at 10.00 am
Patients with FMF (n=25)	17.1 (7.7-32.9)^a	184.5 (55.9-354.8)^b	15.3 (4.5-133.8)^c
Healthy Controls (n=16)		68.3 (11.3-192.3)^d	6.4 (5.1-9.8)^e

The measurements were expressed in median (minimum-maximum). Comparisons between medians were made by Mann-Whitney U test. p<0.001 for a vs b, b vs c, a vs e, d vs e, b vs d, and c vs e; p=0.543 for a vs c.

^* Melatonin levels at 03.30 am and 10.00 am in patients with FMF were measured in attack-free phase.