Fig. (1) 99mTc pertechnate uptake ratios in w.t. and TLR-2 -/- (a), TLR-4 -/- (b) and CD-14 -/- mice given lipidated OspA (c) and w.t. C57Bl/6 mice given 6 or 60 µg of CpG DNA (ODN 1668) (d). Differences in Fig. (1a) significant at all timepoints (day1 p< 0.001, days 2,7 p<0.01); no significant differences in Fig. (2b-d).