Table 2: The Frequency of Methotrexate-Related Adverse Effects in Patients with Rheumatoid Arthritis

n (%)

General  
Fatigue 18(28.1%)
Malaise 14(21.9%)

Gastrointestinal  
Nausea or vomiting 20(31.3%)
Disturbed liver function tests 6(9.4%)

Haematological 2 (3.1%)

Pulmonary 5 (7.8%)

Mucocutaneous 15 (23.4%)

Ear, nose, throat 3 (4.7%)

Neuropsychiatric 2 (3.1%)