Table 3: Total and LDL Cholesterol Levels (Expressed as mg/dL) During the Long-Term Trial by Reginster et al.

Evaluation Time Study Treatment Baseline Values* Values at Each Time Point Delta at Each Time Point
Total Cholesterol
Baseline Placebo (n=70) 224 (40) - -
CGS (n=91) 219 (32) - -
Year 1 Placebo (n=56) 226 (40) 221 (48) -5 (41)
CGS (n=77) 219 (33) 223 (33) 4 (33)
Year 2 Placebo (n=47) 220 (37) 225 (37) 4 (37)
CGS (n=66) 219 (32) 222 (35) 3 (31)
Year 3 Placebo (n=36) 220 (38) 221 (38) 1 (35)
CGS (n=62) 216 (30) 216 (35) 0 (37)
LDL Cholesterol
Baseline Placebo (n=70) 154 (41) - -
CGS (n=92) 161 (34) - -
Year 1 Placebo (n=56) 155 (40) 153 (39) -2 (33)
CGS (n=78) 161 (34) 159 (36) -3 (32)
Year 2 Placebo (n=47) 147 (36) 148 (36) 1 (32)
CGS (n=66) 161 (33) 161 (35) -1 (24)
Year 3 Placebo (n=36) 147 (38) 140 (34) -7 (31)
CGS (n=63) 157 (29) 153 (34) -5 (31)

Values are given as mean (SD); p=not significant in all comparisons.
* In this column, the average of absolute values at baseline for the patients still in study at each yearly clinic visit is given.
CGS=crystalline glucosamine sulfate.