Table 2: Grades of Type I Collagen and Type II Collagen Immunolocalization
Normal
43M
Normal
39F
Normal
12F
OA
42M
OA
49F
OA
54F
OA
55M
OA
58F
OA
65F
OA
66F
OA
70F
Type I
Collagen
GradeS
3
2
1
1
1
1
1
2
1
1
1
GradeI
3
2
1
0
0
0
1
0
0
0
1
Type II
Collagen
GradeS
4
3
2
0
1
0
2
3
1
2
2
GradeI
4
3
2
0
0
0
1
1
0
0
1
GradeS – grade of type I collagen in the surface zone; GradeI – grade of type I collagen in the deep zone; Ages are listed in years; M = male, F = female. The difference of immunolocalization of type I collagen grades between the OA group and the normal control group was statistically significant (p = 0.021). The difference of immunostaining of type II collagen grades between the OA group and the normal control group was statistically significant (p = 0.018).