The Effect of Stopping Smoking on Disease Activity in Rheumatoid Arthritis (RA). Data from BARFOT, a Multicenter Study of Early RA

Table 2: Multiple Logistic Regression Analysis with Outcome EULAR Good vs No or Moderate at 8 Years N= 560

Variable	OR	95% CI	P
Current smokers	0.62	0.37-1.04	0.07
Smoking cessation before inclusion	0.73	0.48-1.10	0.13
Smoking cessation after inclusion	0.44	0.22-0.86	0.02
Age at inclusion	0.99	0.97-1.00	0.07
Disease duration (months)	0.99	0.94-1.03	0.53
DAS28	1.19	1.03-1.37	0.02
Male sex	2.20	1.44-3.36	0.0001
SEI lower white collar	0.97	0.67-1.41	0.87
SEI upper white collar	0.83	0.40-1.71	0.61
SEI self-employed	0.52	1.12-2.20	0.37
SEI Other	0.25	0.06-0.98	0.047
RF	0.60	0.41-0.87	0.007

The variables were baseline data for RF, age, sex, DAS28, and disease duration. Smoking and socioeconomic status were assessed from the 2010 questionnaire. The references for smoking class were never-smokers and for socioeconomic class, manual workers. The patients who stopped smoking after 7 years after enrolment are excluded in this analysis.DAS28 = Disease Activity Score (28 joints), RF = rheumatoid factor, SEI= socioeconomic class.