| Structum® (N=348) | Chondrosulf® (N=344) | All (N=692) | |
|---|---|---|---|
| Sex n (%) Female | 234 (67.2) | 238 (69.2) | 472 (68.2) |
| Age at screening (years)* Min., Max.] | 65.15 (8.59) [49.00, 80.00] | 65.09 (8.59) [50.00, 81.00] | 65.12 (8.58) [49.00, 81.00] |
| Weight (kg) | 75.71 (13.19) | 75.23 (12.38) | 75.47 (12.78) |
| Height (cm) | 165.13 (8.30) | 164.43 (8.77) | 164.78 (8.54) |
| BMI (kg/m2;)* [1] Min., Max.] | 27.67 (3.75) [19.00, 34.00] | 27.74 (3.63) [19.00, 34.00] | 27.71 (3.69) [19.00, 34.00] |
| For females, post-menauposal status: yes n (%) | 230 (98.3) | 235 (98.7) | 465 (98.5) |
| Disease duration (years) | 5.58 (5.37) | 5.65 (5.30) | 5.61 (5.33) |
| Family history of OA n (%) | 51 (15.3) | 54 (16.6) | 105 (15.9) |
| Target knee: right n (%) | 178 (51.1) | 181 (52.6) | 359 (51.9) |
| Effusion in target knee: yes n (%) | 17 (4.9) | 11 (3.2) | 28 (4.0) |
| OA in the non target knee: yes n (%) | 249 (71.6) | 267 (77.6) | 516 (74.6) |
| Hip OA: yes n (%) | 22 (6.3) | 22 (6.4) | 44 (6.4) |
| Cervical spine OA: yes n (%) | 71 (20.6) | 55 (16.1) | 126 (18.3) |
| Lumbar spine OA: yes n (%) | 106 (30.6) | 92 (26.9) | 198 (28.8) |
| Hand OA: yes n (%) | 35 (10.1) | 17 (5.0) | 52 (7.5) |
|
Kellgren-Lawrence grade n (%) Grade II Grade III |
244 (70.1) 104 (29.9) |
238 (69.2) 106 (30.8) |
482 (69.7) 210 (30.3) |
| Non pharmacological treatment (target knee) n (%) | 13 (3.7) | 13 (3.8) | 26 (3.8) |
| Previous IA corticosteroid injection in target knee: yes n (%) | 11 (3.2) | 8 (2.3) | 19 (2.7) |
| Previous HA injections: yes n (%) | 15 (4.3) | 11 (3.2) | 26 (3.8) |