| Variable | 5 Years of Follow-Up | 8 Years of Follow-Up | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | p-Value | OR | 95% CI | p-Value | |
| Age at inclusion | 0.99 | 0.97-1.0 | 0.06 | 0.98 | 0.97-1.00 | 0.045 |
| Disease duration, months | 0.95 | 0.92-0.99 | 0.02 | 1.0 | 0.95-1.06 | 0.88 |
| Male sex | 2.23 | 1.50-3.32 | 0.000 | 2.85 | 1.74-4.68 | 0.000 |
| Blue-collar | 0.72 | 0.37-1.40 | 0.33 | 1.01 | 0.44-2.34 | 0.98 |
| Lower white-collar | 0.91 | 0.47-1.77 | 0.77 | 0.98 | 0.42-2.29 | 0.97 |
| Self-employed | 0.76 | 0.18-3.27 | 0.71 | 0.78 | 1.13-4.73 | 0.78 |
| Other | 0.15 | 0.04-0.67 | 0.01 | 0.52 | 0.11-2.49 | 0.41 |
| Non-immigrant | 0.84 | 0.43-1.65 | 0.62 | 0.78 | 0.32-1.86 | 0.57 |
| RF | 0.98 | 0.69-1.39 | 0.90 | 0.56 | 0.36-0.88 | 0.01 |
| Current smoker | 0.64 | 0.42-0.98 | 0.04 | 0.50 | 0.30-0.83 | 0.008 |
| Previous smoker | 0.76 | 0.51-1.12 | 0.17 | 0.83 | 0.51-1.34 | 0.44 |
| Cumulative number of previous DMARDs and biologics | 0.64 | 0.56-0.74 | 0.000 | 0.63 | 0.54-0.74 | 0.000 |
| HAQ | 1.26 | 0.95-1.69 | 0.11 | 2.01 | 1.38-2.93 | 0.000 |
| BMI < 19 | 0.94 | 0.30-2.92 | 0.91 | 0.83 | 0.22-3.10 | 0.78 |
| BMI 26-30 | 0.98 | 0.67-1.44 | 0.91 | 0.70 | 0.44-1.13 | 0.14 |
| BMI > 30 | 0.76 | 0.47-1.24 | 0.27 | 0.59 | 0.33-1.05 | 0.07 |