Profiling of HLA-B Alleles for Association Studies with Ankylosing Spondylitis in the Chinese Population

Table 1: Allele Frequency of HLA-B in Han Chinese AS Cases and Controls

Alleles	AS	%	Control	%	p	OR
B^*07	1	0.1	12	1.8	0.0018	0.08
B^*08	2	0.3	5	0.7	0.237	0.38
B^*13	39	5.5	78	11.4	7.4 x 10^-5	0.45
B^*14	3	0.4	1	0.2	0.334	2.91
B^*15	51	7.2	120	17.5	<1 x10^-7	0.36
B^*18	2	0.3	1	0.2	0.584	1.93
B^*27	336	47.5	26	3.8	<1 x10^-7	22.86
B^*35	14	2.0	37	5.4	6.6 x10^-4	0.35
B^*37	2	0.3	4	0.6	0.389	0.48
B^*38	12	1.7	20	2.9	0.126	0.57
B^*39	15	2.1	10	1.5	0.356	1.46
B^*40	73	10.3	88	12.9	0.136	0.78
B^*41	0	0	1	0.1	0.309	0
B^*44	9	1.3	16	2.3	0.134	0.54
B^*45	0	0	7	1.0	0.007	0
B^*46	36	5.1	68	10	5.7 x10^-4	0.49
B^*48	12	1.7	11	1.6	0.899	1.05
B^*50	2	0.3	0	0	0.164	NA
B^*51	29	4.1	60	8.8	3.6 x10^-4	0.44
B^*52	12	1.7	19	2.8	0.171	0.6
B^*53	1	0.1	0	0	0.325	NA
B^*54	10	1.4	19	2.8	0.075	0.5
B^*55	12	1.7	14	2.1	0.628	0.83
B^*56	1	0.1	4	0.6	0.167	0.24
B^*57	4	0.6	4	0.6	0.96	0.97
B^*58	25	3.5	50	7.3	0.0018	0.46
B^*59	0	0	4	0.6	0.042	0
B^*67	3	0.4	3	0.4	0.966	0.97
B^*78	1	0.1	2	0.3	0.543	0.48
B^*81	1	0.1	0	0	0.325	NA

^* A p-value less than 0.00167 is significant after correction for multiple comparison.