Table 1: Patients Baseline Characteristics

Age (Years ± SD) Group 1 n=13 (Biologic-Naïve) 50.32 ±4.57 Group 2 n=12 (Anti-TNFα Failed) 52±6.09 P Value p=0.08

Sex
 Male 1 (4%) 1 (4%)
 Female 12 (48%) 11 (44%)

DMARD numbers
 One (1) used 5 (20%) 7 (28%)
 2 ≥ more frequently used 8 (32%) 5 (20%) p<0.005

Duration of the disease years ± SD 5±1.89 10.04 ± 3.92 p<0.001

ESR baseline (M±SD) 47.39 ± 7.69 35±5.12 p<0.001

CRP baseline mg/dl: (M±SD) 12.25±2.68 9±1.08 p<0.001

DAS28 baseline (M±SD) 4.93±0.37 3.78±0.12 p=0.34

HAQ baseline: (M±SD) 2.33±0,21 2.55±0.11 p=0.08

Rheumatoid Factor positive (%) 11 (84.6%) 12 (100%) p=0.81

Anti CCP positive >25 Ui/ml 8 (61.5%) 9 (75%) p=0.1

SD: standard deviation. DAS: Disease Activity Score. HAQ: Health Assessment Questionnaire. ESR: erythrocyte sedimentation rate. CPR: “C” reactive protein, RF-Test: Screening Test for Rheumatoid Factor. Anti-CCP: Antibodies against citrullinated peptides. DMARD: disease-modifying anti-rheumatic drugs.