LETTER TO THE EDITOR Subcutaneous (SC) Methotrexate (MTX) is Better and Well-Tolerable than Oral MTX in Rheumatoid Arthritis Patients, Switched from Oral to SC Administration Due to Gastrointestinal Side Effects

Table 1: The disease activity parameters before switching from oral to subcutaneous MTX and at first and third months after switching.

	Last Visit of Oral MTX n=80	1st Month Visit After sc MTX n=80	3rd Month Visit After sc MTX n=80	p
DAS28	4.0±0.9	3.6±0.8	3.4±0.8	<0.01
ESR	42.5±21	33.8±17.4	29.7±15	<0.05
CRP	2.3±2.8	1.4±1.4	0.8±0.9	<0.05
pain by VAS	66.9±18.9	53.9±14.2	51.6±14.4	<0.05