Table 2: Clinical characteristics according to sex before and after treatment.

  Female Male
    0 Weeks 6 Months p 0 Weeks 6 Months p
SDAI 22.1 ± 11.9 8.9 ± 7.8 0.000* 27.9 ± 11.7 12.7 ± 8.6 0.000*
mHAQ 0.46 ± 0.50 0.32 ± 0.45 0.000* 0.59 ± 0.48 0.43 ± 0.62 0.166*
HAM-D 6.2 ± 4.8 3.8 ± 4.1 0.000* 5.8 ± 4.3 4.8 ± 3.9 0.148*
HAM-D>7 31 (22.5%) 15 (10.9%) 0.000** 1 (4.3%) 5 (21.7%) 0.317**
SF-36 Physical functioning 29.3 ± 17.6 36.1 ± 17.2 0.000* 25.8 ± 17.7 29.4 ± 16.2 0.122*
Role function (physical) 31.9 ± 16.1 38.0 ± 15.1 0.000* 28.7 ± 15.6 32.8 ± 14.9 0.182*
Pain 35.6 ± 9.1 41.4 ± 9.4 0.000* 33.2 ± 8.6 37.6 ± 10.6 0.065*
General health perception 39.0 ± 9.1 42.9 ± 9.8 0.000* 34.8 ± 8.1 36.0 ± 7.4 0.293*
Fatigue 43.2 ± 11.5 47.1 ± 11.0 0.000* 41.2 ± 10.9 43.4 ± 10.6 0.207*
Social functioning 40.3 ± 14.7 45.0 ± 12.4 0.000* 36.4 ± 15.7 38.6 ± 13.4 0.272*
Role function (emotional) 38.9 ± 16.3 42.6 ± 15.1 0.000* 33.8 ± 16.4 37.3 ± 14.4 0.236*
Mental health 46.6 ± 11.2 49.6 ± 10.5 0.000* 39.2 ± 11.1 41.4 ± 10.8 0.260*

Mean ± standard deviation.SDAI: Simplified Disease Activity Index.mHAQ: modified health assessment questionnaire.HAM-D: Hamilton Depression Rating Scale.SF-36: short form-36.* analysis using the paired t-test.** analysis using the Wilcoxon signed-rank test.