Table 3: Determinants of in-hospital mortality.

Variables Total P-value NIPPV prior to IMV Only IMV p-value
All Patients N=54
Deaths 34
[63.0%]		 N=27
Deaths 17
[63.0%]		 N=27
Deaths 17
[63.0%]		 1.00
Deaths/n Deaths/n Deaths/n
BMI
<26.9
26.9+
13/27 [48.1%]
21/27 [77.8%]		 0.047
5/12 [41.7%]
12/15 [80.0%]
8/15 [53.3%]
9/12 [75.0%]
0.70
1.00
Age
<65
65+
11/22 [50.0%]
23/32 [71.9%]		 0.15
3/9 [33.3%]
14/18 [77.8%]
8/13 [61.5%]
9/14 [64.3%]
0.39
0.45
Gender
Female
Male
15/24 [62.5%]
19/30 [63.3%]		 1.00
9/13 [69.2%]
8/14 [57.1%]
6/11 [54.5%]
11/16 [68.8%]
0.68
0.71
ILD Subtype
IPF
CTDs
Sarcoidosis
Other
7/8 [87.5%]
12/17 [70.6%]
1/7 [14.3%]
14/22 [63.6%]		 0.027
1/2 [50.0%]
5/8 [62.5%]
1/4 [25.0%]
10/13 [76.9%]
6/6 [100.0%]
7/9 [77.8%]
0/3 [0.0%]
4/9 [44.4%]
0.25
0.62
1.00
0.19
ILD Duration
ILD <1 year
ILD ≥1 year
19/24 [79.2%]
15/30 [50.0%]		 0.046
10/11 [90.9%]
7/16 [43.8%]
9/13 [69.2%]
8/14 [57.1%]
0.33
0.72
Supplemental O2
Prescribed
Not prescribed
12/25 [48.0%]
22/29 [75.9%]		 0.049
8/15 [53.3%]
9/12 [75.0%]
4/10 [40.0%]
13/17[76.5%]
0.69
1.00
Pulmonary Hypertension
Present
Not Present
18/28 [64.3%]
16/26 [61.5%]		 1.00
7/14 [50.0%]
10/13 [76.9%]
11/14 [78.6%]
6/13 [46.2%]
0.24
0.23
History of CTD
Present
Not Present
16/27 [59.3%]
18/27 [66.7%]		 0.78
8/14 [57.1%]
9/13 [69.2%]
8/13 [61.5%]
9/14 [64.3%]
1.00
1.00
Cause of ARF
Pneumonia/Sepsis
ILD Exacerbation
All others
21/33 [63.6%]
7/9 [77.8%]
6/12 [50.0%]		 0.45
9/17 [52.9%]
5/6 [83.3%]
3/4 [75.0%]
12/16 [75.0%]
2/3 [66.7%]
3/8 [37.5%]
0.28
1.00
0.55
SVTs
Sinus Tachycardia
All Other SVTs
11/21 [52.4%]
20/25 [80.0%]		 0.06
4/7 [57.1%]
12/15 [80.0%]
7/14 [50.0%]
8/10 [80.0%]
1.00
1.00
Vasopressor
Used
Not used
30/44 [68.2%]
2/8 [25.0%]		 0.043
15/22 [68.2%]
0/3 [0.0%]
15/22 [68.2%]
2/5 [40.0%]
1.00
0.46
Pulmonary Vasodilator
Used
Not Used
15/22 [68.2%]
13/26 [50.0%]		 0.25
5/8 [62.5%]
8/15 [53.3%]
10/14 [71.4%]
5/11 [45.5%]
1.00
1.00
Steroid Use
Pulse/Stress Dose
Other Dose
19/22 [86.4%]
10/26 [38.5%]		 0.001
11/13 [84.6%]
6/14 [42.9%]
8/9 [88.9%]
4/12 [33.3%]
1.00
0.70

Legend: Column 3 represents p-value for the mortality of the total number of patients as a comparison of death rate prior to cohort stratification. Column 6 represents p-values for mortality of patients compared within each strata of both NIPPV prior to IMV and Only IMV.