Table 5: Determinants of one-year mortality.

Variables Total P-value NIPPV prior to IMV Only IMV P-value
All Patients N=54
Deaths 44
[81.5%]
N=27
Deaths 23
[85.2%]
N=27
Deaths 21
[77.8%]
0.73
Deaths/n Deaths/n Deaths/n
BMI
<26.9
26.9+

20/27 [74.1%]
24/27 [88.9%]
0.29
9/12 [75.0%]
14/15 [93.3%]

11/15 [73.3%]
10/12 [83.3%]

1.00
0.57
Age
<65
65+

16/22 [72.7%]
28/32 [87.5%]
0.28
5/9 [55.6%]
18/18 [100.0%]

11/13 [84.6%]
10/14 [71.4%]

0.18
0.028
Gender
Female
Male

19/24 [79.2%]
25/30 [83.3%]
0.74
11/13 [84.6%]
12/14 [85.7%]

8/11 [72.7%]
13/16 [81.3%]

0.63
1.00
ILD Subtype
IPF
CTD
Sarcoidosis
Other

8/8 [100.0%]
13/17 [76.5%]
2/7 [28.6%]
21/22 [95.5%]
0.001
2/2 [100.0%]
6/8 [75.0%]
2/4 [50.0%]
13/13 [100.0%]

6/6 [100.0%]
7/9 [77.8%]
0/3 [0.0%]
8/9 [88.9%]

1.00
1.00
0.43
0.41
ILD Presence
<1 year
≥1 year

22/24 [91.7%]
22/30 [73.3%]
0.16
11/11 [100.0%]
12/16 [75.0%]

11/13 [84.6%]
10/14 [71.4%]

0.48
1.00
Pulmonary Hypertension
Present
Not Present

23/28 [82.1%]
21/26 [80.8%]
1.00
10/14 [71.4%]
13/13 [100.0%]

13/14 [92.9%]
8/13 [61.5%]

0.33
0.039
History of Connective Tissue Disease
Present
Not Present

18/27 [66.7%]
26/27 [96.3%]
0.011
10/14 [71.4%]
13/13 [100.0%]

8/13 [61.5%]
13/14[92.9%]

0.69
1.00
Cause of ARF
Pneumonia/Sepsis
ILD Exacerbation
All others

28/33 [84.8%]
9/9 [100.0%]
7/12 [58.3%]
0.45
14/17 [82.4%]
6/6 [100.0%]
3/4 [75.0%]

14/16 [87.5%]
3/3 [100.0%]
4/8 [50.0%]

1.00
1.00
0.58
SVTs
Sinus Tachycardia
All Other SVTs

15/21 [71.4%]
24/25 [96.0%]
0.037
6/7 [85.7%]
14/15 [93.3%]

9/14 [64.3%]
10/10 [100.0%]

0.61
1.00
Vasopressor
Used
Not used

38/44 [86.4%]
4/8 [50.0%]
0.035
19/22 [86.4%]
2/3 [66.7%]

19/22 [86.4%]
2/5 [40.0%]

1.00
1.00
Pulmonary Vasodilator
Used
Not Used

19/22 [86.4%]
19/26 [73.1%]
0.31
6/8 [75.0%]
13/15 [86.7%]

13/14 [92.9%]
6/11 [54.5%]

0.53
0.09
Steroid Use
Pulse/Stress Dose
Other Dose

20/22 [90.9%]
18/26 [69.2%]
0.08
12/13 [92.3%]
11/14 [78.6%]

8/9 [88.9%]
7/12 [58.3%]

1.00
0.40

Legend: Column 3 represents p-value for the mortality of the total number of patients as a comparison of death rate prior to cohort stratification. Column 6 represents p-values for mortality of patients compared within each strata of both NIPPV prior to IMV and Only IMV.