Table 2: Summary of the evidence outlining the potential role of Vitamin D in COVID-19.

References Name of the Study Findings/Results
Wimalawansa, S.J. et al. [39] The global epidemic of coronavirus--COVID-19: What we can do to minimize risks 5000 IU/d. Individuals prone to COVID-19 need to have their VD levels more than 40-60ng/ml by supplementing 10,000IU/day for a few weeks followed by tapering to 5000IU/day.
Nair et al. [40] Vitamin D: The “sunshine” vitamin Supportive data for the effective role of VD in decreasing the risk of COVID-19 could be highlighted by increased
case-fatality rates with chronic disease comorbidity and age, in which lower concentrations of
25(OH) D have been reported.
Epidemiology Working Group for NCIP Epidemic Response, Chinese Center for Disease Control and Prevention [41]. The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) in China Since VD levels decrease with age, it may be important to assess the risk of VD as a factor owing to its high case fatality in older age groups.
Grant et al. [42] Evidence that Vitamin D Supplementation Could
Reduce the Risk of Influenza and COVID-19 Infections
and Deaths
Treatment of Community Acquired Pneumonia (CAP) with VD did not significantly result in complete resolution but led to decreased concentration of IL-6, CRP in diabetic patients. VD contributes to the increased risk of ARDS development.
Moraes et al. [43]
Lee et al. [44]
1. Vitamin D deficiency is independently associated with mortality among critically ill patients.
2. Vitamin D deficiency in critically ill patients.
There may be an etiological association between low VD levels, positive blood cultures, and mortality in critically ill patients admitted to ICU.