| SOFA based Scoring Systems | Respiratory | Cardiovascular | Neurological | Hepatic | Renal | Coagulation | |
|---|---|---|---|---|---|---|---|
| Original SOFA Score | - PaO2/FiO2 ratio - Respiratory support considered for values 3 and 4 |
- MAP<70 mm Hg - Use of vasopressors & dobutamine |
- Glasgow coma scale | - Bilirubin (mg/dl or umol/L) | - Creatinine (mg/dl or umol/L) - Urinary output |
- Platelets (x 1000/mm3) | |
| Modified SOFA (mSOFA) | - Respiratory support not included | - Blood pressure not included - Number of vasopressors |
-- | - Bilirubin (mg/dl) | - Creatinine (mg/dl) | Same as original SOFA | |
| Modified SOFA (MSOFA) | - SpO2/FiO2 ratio - Respiratory support considered for values 3 and 4 |
Same as original SOFA | Same as original SOFA | - Scleral icterus - Presence of jaundice |
Same as original SOFA | -- | |
| Modified cardiovascular SOFA (mCV-SOFA) | Same as original SOFA | - Lactate levels - Shock index - Number of vasopressors |
Same as original SOFA | Same as original SOFA | Same as original SOFA | Same as original SOFA | |
| Extra-renal SOFA | Same as original SOFA | Same as original SOFA | Same as original SOA | Same as original SOFA | -- | Same as original SOFA | |
| Chronic Liver Failure (CLIF-SOFA) | - PaO2/FiO2 ratio - SpO2/FiO2 ratio - Respiratory support not included |
- Use of vasopressors | - Presence of grade II or IV hepatic encephalopathy | - Bilirubin (mg/dl) | - Creatinine (mg/dl) - Renal replacement therapy |
- Platelets (x 1000/mm3) - International normalized ratio |
|
| Mexican SOFA (Mex SOFA) | - SpO2/FiO2 ratio - Respiratory support considered for values 3 and 4 |
Same as original SOFA | -- | Same as original SOFA | Same as original SOFA | Same as original SOFA | |
| Quick SOFA (qSOFA) |
- Respiratory rate ≥22/min | - Systolic blood pressure ≤100 mmHg | - Change in mental status | -- | -- | -- | |
| qSOFA and Plasma Lactic Acid Levels (LqSOFA) | - Respiratory rate ≥22/min | - Systolic blood pressure ≤100 mmHg - Lactate levels |
- Change in mental status | -- | -- | -- | |
| SOFA in Hematological Malignancies (SOFA-HM) | Same as original SOFA | Same as original SOFA | Same as original SOFA | Same as original SOFA | Same as original SOFA | Same as original SOFA | |
| Additional System - Infection: Documented infection within 90 days | |||||||
| SOFA with Richmond Agitation-Sedation scale (SOFA RASS) | Same as original SOFA | Same as original SOFA | Richmond Agitation-Sedation scale | Same as original SOFA | Same as original SOFA | Same as original SOFA | |
| Pediatric SOFA (pSOFA) | - PaO2/FiO2 ratio OR SpO2/FiO2 ratio - Respiratory support considered for values 3 and 4 |
- MAP (age-adjusted) - Vasoactive agents (age-adjusted) |
Same as original SOFA | Same as original SOFA | - Creatinine (age-adjusted) | Same as original SOFA | |