Table 1.: CT Score, Smoking Index and Pulmonary Function Test in Three CLE Subtypes

Subtype (n) A (20) B (45) C (8) p Value
Male/Female 15/5 40/5 8/0
Smoking index (pack-years) 33.8 (17.5-50.0) 55.0 (41.1-75.0) 49.4 (44.0-73.3) <0.05
age (y/o) 74.0 (68.5-82) 72.0 (63.5-75.3) 68.5 (63.0-71.5) NS
CT score (points) 6.0 (6-9.5) 11.0 (7.8-14.0) 19.0(10.0-20.5) <0.05
%VC (%) 117.9(101.2-124.7) 114.8 (103.6-123.9) 98.25 (81.5-120.8) NS
FEV1% (%) 64.2 (49.5-75.7) 58.9 (43.7-70.5) 38.3 (33.4-43.0) <0.05
%FEV1 (%) 93.4 (72.2-115.6) 88.5 (64.5-106.9) 48.3 (38.3-71.3) <0.05
FVC (L) 3.1 (2.7-3.8) 3.5 (3.0-4.0) 3.2 (2.5-3.5) NS
RV/TLC (%) 35.8 (30.0-44.5) 37.4 (32.7-45.3) 43.3 (37.6-57.7) NS
V50 (L/sec) 1.1 (0.6-2.2) 1.1 (0.4-1.9) 0.4 (0.3-0.7) NS
V25 (L/sec) 1.2 (0.6-2.3) 0.3 (0.1-0.5) 0.2 (0.1-0.3) NS
MMF (L) 0.8 (0.4-1.7) 0.8 (0.3-1.4) 0.3 (0.3-0.6) NS
%DLco/VA (%) 70.4 (56.7-76.3) 47.2 (36.7-58.1) 29.0 (19.0-67.4) <0.05
%DLco (%) 62 (46.0-72.3) 43.3 (36.2-55.4) 35.7 (21.3-60.7) <0.05

There were significant differences in CT score, smoking index and pulmonary function test including FEV1%, %FEV1, %DLco/VA and %DLco. The data was expressed as median with first quartile point (25 percentile) and third quartile point (75 percentile).