Fig. (5) Effects of rhEGF on tumor growth delay of ionizing radiation in Balb/c mice implanted with EMT-6 cells.Each group was irradiated (if indicated) and then treated as indicated for 7 consecutive days, three times a day, following the irradiation. Vehicle only = vehicle (100μl) without irradiation; Vehicle+IR(10Gy) = vehicle (100μl) with 10 Gy; Vehicle+IR(20Gy) = vehicle (100μl) with 20 Gy; EGF only = EGF (1.0 mg/kg) without irradiation; EGF+IR(10Gy) = EGF (1.0 mg/kg) with 10 Gy; EGF+IR(20Gy) = EGF (1.0 mg/kg) with 20 Gy. The data are means ± SD of three independent experiments. rhEGF, whether given alone or combined with radiation, did not stimulate tumor growth.