Table 1: Baseline and End of Treatment Characteristics of 35 Patients with Nonalcoholic Steatohepatitis Treated with Betaine

BASELINE END OF TREATMENT p value
Weight (kilograms) 97.2 +/- 3.15 97.4 +/- 3.63 NS
ALT (U/L) 109 +/- 14.4 45 +/- 10.8 p < 0.05
AST (U/L) 98.1 +/- 21.2 36.9 +/- 5.9 p < 0.05
Alk phos (U/L) 122 +/- 13.7 101 +/- 14.6 p < 0.05
Bilirubin (mg/dl) 0.6 +/- 0.1 0.49 +/- 0.05 p < 0.05
Homocysteine (micromoles/L) 7.72 +/- 0.37 7.42 +/- 0.42 NS
Steatosis 2.28 +/- 0.12 1.13 +/- 0.15 p < 0.05
Inflammation 1.31 +/- 0.12 0.71 +/- 0.11 p < 0.05
Fibrosis 2.09 +/- 0.24 1.29 +/-0.24 p < 0.05

ALT: alanine aminotransferase; AST: aspartate aminotransferase; Alk phos: alkaline phosphatase; NS: not significant. Data expressed as means +/- standard deviation.