Single Nucleotide Variants in A Family of Monozygotic Twins Discordant for the Phenotype Congenital Megaureter: A Genomic Analysis

Table 3: Candidate variants in the proband after data filtering.

	Frequency
Total number of SNVs in the proband	40,123
*Number of previously described SNVs [excluded]**	36,165
SNVs identified as coding silent, intergenic, intronic, UTR and synonymous mutations, quality score < 20, PhyloP score < 3 [excluded]	3,702
Remaining candidate SNVs	256

*Project 1000 genomes [³²], Exome Variant Server NHLBI GO Exome Sequencing Project [ESP], dbSNV database [³³]. November 2015.