Organ | Definition |
---|---|
Liver Failure | SOFA ≥3 (serum bilirubin ≥ 6 mg/dL) or Maddrey’s DF >32 |
Renal Failure | Defined as AKI, according to the Acute Kidney Injury Network criteria |
Nervous system failure | SOFA ≥3 (Glasgow Coma Scale ≤9) |
Respiratory failure | SOFA ≥3 (PaO2/FiO2 <200 and mechanically ventilated) |
Circulatory failure | SOFA ≥3 (use of norepinephrine, epinephrine, or dopamine [dopamine >5 μg/kg/min]) |
Coagulation failure | SOFA ≥3 (platelet count <50,000/μL) |