Fig. (1) ^*Bisphosphonates: Zolendronate is superior to pamidronate in reversing hypercalcemia of malignancy ^**Calcitonin: Usually serum calcium (Ca) levels are checked several hours after administration of calcitonin, if hypocalcemia response is noted, administration is continued. Calcitonin is also given with bisphosphonates for Ca>14 mg/dL if symptomatic ^***Furosemide: In the absence of renal failure or heart failure, loop diuretic therapy to directly increase calcium excretion is not recommended, because of potential complications and the availability of drugs that inhibit bone resorption, which is primarily responsible for the hypercalcemia [14]