The Effectiveness of N-acetylcysteine in Alleviating Kidney Dysfunction in Ifosfamide-treated Rats

Table 2: The results of parameters determined in the serum.

	Group 1	Group 2	Group 3
Creatinine [mg/dL]	0.24 ± 0.04	0.25 ± 0.04	0.21 ± 0.44
BUN [mg/dL]	18.50 ± 3.34	21.86 ± 2.10^a*	18.38 ± 3.66^b*
Urea [mg/dL]	37.15 ± 4.86	46.84 ± 4.50^a#	39.38 ± 7.85^b*
BUN/urea ratio	78.00 ± 17.83	88.67 ± 24.48	87.71 ± 14.66
Uric acid [mg/dL]	1.63 ± 0.68	1.06 ± 0.59	1.15 ± 0.69
Total protein [g/dL]	4.73 ± 0.35	5.70 ± 0.19^a#	5.30 ± 0.19
Na [mmol/L]	147.63 ± 0.92	148.25 ± 3.11	146.00 ± 2.00
K [mmol/L]	5.82 ± 0.70	6.38 ± 1.18	5.50 ± 1.00
Cl [mmol/L]	104.88 ± 0.84	106.00 ± 2.27	104.00 ± 2.56
CysC [µg/mL]	0.84 ± 0.29	3.48 ± 0.41^a#	2.86 ± 0.79

BUN – blood nitrogen urea; CysC – Cystatin C; ^a* P<0.05; ^a# P<0.001 for paired groups 1-2; ^b* P<0.05 for paired groups 2-3.