Table 1: Demographics of Patients at Presentation

  Time Period
1980-2000 2001-2006
No. of patients 1162 187
Gender ratio (male/female) 1.4 1.3
Age of disease onset, years (mean±SD) 6.7±3.9 6.8±47
Duration before the beginning of the
treatment in clinic, months (mean±SD)
11±13 16±24
Follow-up, months (mean±SD) 65±44 30±17